Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells

RNA splicing is a fundamental process for protein synthesis. Recent studies have reported that drugs that inhibit splicing have cytotoxic effects on various tumor cell lines. In this report, we demonstrate that depletion of SNW1, a component of the spliceosome, induces apoptosis in breast cancer cel...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Sato, Naoki, Maeda, Masao, Sugiyama, Mai, Ito, Satoko, Hyodo, Toshinori, Masuda, Akio, Tsunoda, Nobuyuki, Kokuryo, Toshio, Hamaguchi, Michinari, Nagino, Masato, Senga, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329010/
https://ncbi.nlm.nih.gov/pubmed/25450007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.366
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