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miR‐181a induces sorafenib resistance of hepatocellular carinoma cells through downregulation of RASSF1 expression

Sorafenib, a multi‐kinase inhibitor, is the only standard clinical drug for patients with advanced hepatocellular carcinoma (HCC); however, development of sorafenib resistance in HCC often prevents its long‐term efficacy. Therefore, novel targets and strategies are urgently needed to improve the ant...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Azumi, Junya, Tsubota, Toshiaki, Sakabe, Tomohiko, Shiota, Goshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021022/
https://ncbi.nlm.nih.gov/pubmed/27384977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13006
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