miR-126-3p contributes to sorafenib resistance in hepatocellular carcinoma via downregulating SPRED1

BACKGROUND: Sorafenib can prolong the survival of patients with advanced hepatocellular carcinoma (HCC). However, drug resistance remains the main obstacle to improving its efficiency. This study aimed to explore the likely molecular mechanism of sorafenib resistance. METHODS: Differentially express...

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Enregistré dans:
Détails bibliographiques
Publié dans:Ann Transl Med
Auteurs principaux: Tan, Wenliang, Lin, Zhirong, Chen, Xianqing, Li, Wenxin, Zhu, Sicong, Wei, Yingcheng, Huo, Liyun, Chen, Yajin, Shang, Changzhen
Format: Artigo
Langue:Inglês
Publié: AME Publishing Company 2021
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859776/
https://ncbi.nlm.nih.gov/pubmed/33553331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-2081
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