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IGF1R mutation analysis in short children with Silver-Russell syndrome features

The insulin-like growth factor 1 receptor (IGF1R) is a key factor in intrauterine and postnatal growth by mediating the biological function of IGF-I. Mutations of IGF1R gene are usually associated with growth retardation, but the clinical picture of IGF1R mutation carriers is heterogeneous. Indeed,...

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Detalhes bibliográficos
Publicado no:J Pediatr Genet
Main Authors: Soellner, Lukas, Spengler, Sabrina, Begemann, Matthias, Wollmann, Hartmut A., Binder, Gerhard, Eggermann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020970/
https://ncbi.nlm.nih.gov/pubmed/27625849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/PGE-13059
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