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Protective mechanisms of microRNA-27a against oxygen-glucose deprivation-induced injuries in hippocampal neurons

Hypoxic injuries during fetal distress have been shown to cause reduced expression of microRNA-27a (miR-27a), which regulates sensitivity of cortical neurons to apoptosis. We hypothesized that miR-27a overexpression attenuates hypoxia- and ischemia-induced neuronal apoptosis by regulating FOXO1, an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neural Regen Res
Prif Awduron: Cai, Qun, Wang, Ting, Yang, Wen-jie, Fen, Xing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Medknow Publications & Media Pvt Ltd 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020828/
https://ncbi.nlm.nih.gov/pubmed/27651777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.189194
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