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Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose-deprivation
Oxidative stress is a mediator of cell death following cerebral ischemia/reperfusion and heme toxicity which can be an important pathogenic factor in acute brain injury. Induced expression of Phase II detoxification enzymes through activation of the anti-oxidant response element (ARE)/Nrf2 pathway h...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037525/ https://ncbi.nlm.nih.gov/pubmed/19998483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22307 |
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