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Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose-deprivation

Oxidative stress is a mediator of cell death following cerebral ischemia/reperfusion and heme toxicity which can be an important pathogenic factor in acute brain injury. Induced expression of Phase II detoxification enzymes through activation of the anti-oxidant response element (ARE)/Nrf2 pathway h...

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Main Authors: Soane, Lucian, Dai, Wei Li, Fiskum, Gary, Bambrick, Linda L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037525/
https://ncbi.nlm.nih.gov/pubmed/19998483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22307
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