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Evolution and Characterization of a Benzylguanine-binding RNA Aptamer
Repurposing the “protein-labeling toolkit” for RNA research could be a pragmatic approach for developing new RNA-labeling methods. We have evolved an RNA aptamer that tightly binds benzylguanine (bG), the key ligand for the protein SNAP-tag. The aptamer tightly binds bG fluorophores and can be purif...
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| Publicado en: | Chem Commun (Camb) |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5020705/ https://ncbi.nlm.nih.gov/pubmed/26538152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07605f |
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