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Necroptosis Is an Important Severity Determinant and Potential Therapeutic Target in Experimental Severe Pancreatitis
BACKGROUND & AIMS: Severe acute pancreatitis is characterized by acinar cell death and inflammation. Necroptosis is an aggressive and proinflammatory mode of cell death that can be prevented by necrostatin-1 administration or receptor-interacting protein kinase (RIP3) deletion. METHODS: Mouse pa...
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| Publié dans: | Cell Mol Gastroenterol Hepatol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5020563/ https://ncbi.nlm.nih.gov/pubmed/27642624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.04.002 |
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