Necroptosis Is an Important Severity Determinant and Potential Therapeutic Target in Experimental Severe Pancreatitis

BACKGROUND & AIMS: Severe acute pancreatitis is characterized by acinar cell death and inflammation. Necroptosis is an aggressive and proinflammatory mode of cell death that can be prevented by necrostatin-1 administration or receptor-interacting protein kinase (RIP3) deletion. METHODS: Mouse pa...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Gastroenterol Hepatol
Main Authors: Louhimo, Johanna M., Steer, Michael L., Perides, George
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020563/
https://ncbi.nlm.nih.gov/pubmed/27642624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.04.002
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki