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Improving the performance of the PLB index for ligand-binding site prediction using dihedral angles and the solvent-accessible surface area

Protein ligand-binding site prediction is highly important for protein function determination and structure-based drug design. Over the past twenty years, dozens of computational methods have been developed to address this problem. Soga et al. identified ligand cavities based on the preferences of a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Cao, Chen, Xu, Shutan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020399/
https://ncbi.nlm.nih.gov/pubmed/27619067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33232
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