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Relative Solvent Accessible Surface Area Predicts Protein Conformational Changes upon Binding

Protein interactions are often accompanied by significant changes in conformation. We have analyzed the relationships between protein structures and the conformational changes they undergo upon binding. Based upon this, we introduce a simple measure, the relative solvent accessible surface area, whi...

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Main Authors: Marsh, Joseph A., Teichmann, Sarah A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145976/
https://ncbi.nlm.nih.gov/pubmed/21645856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.03.010
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