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The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms)
The Fischer 344 (F344) rat was used by the National Toxicology Program (NTP) for over 5 decades for toxicity and carcinogenicity studies. However, in 2006, the NTP decided to switch to a different rat stock due largely to high background control incidences of Leydig cell tumors (LCTs) and mononuclea...
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| Pubblicato in: | Crit Rev Toxicol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5020328/ https://ncbi.nlm.nih.gov/pubmed/27278595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10408444.2016.1174669 |
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