Involvement of Histone Lysine Methylation in p21 Gene Expression in Rat Kidney In Vivo and Rat Mesangial Cells In Vitro under Diabetic Conditions

Diabetic nephropathy (DN), a common complication associated with type 1 and type 2 diabetes mellitus (DM), characterized by glomerular mesangial expansion, inflammation, accumulation of extracellular matrix (ECM) protein, and hypertrophy, is the major cause of end-stage renal disease (ESRD). Increas...

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Publicado en:J Diabetes Res
Autores principales: Li, Xiangjun, Li, Chaoyuan, Li, Xiaoxia, Cui, Peihe, Li, Qifeng, Guo, Qiaoyan, Han, Hongbo, Liu, Shujun, Sun, Guangdong
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019898/
https://ncbi.nlm.nih.gov/pubmed/27652271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3853242
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