Histone Lysine Methylation in TGF-β1 Mediated p21 Gene Expression in Rat Mesangial Cells

Transforming growth factor beta1- (TGF-β1-) induced p21-dependent mesangial cell (MC) hypertrophy plays a key role in the pathogenesis of chronic renal diseases including diabetic nephropathy (DN). Increasing evidence demonstrated the role of posttranscriptional modifications (PTMs) in the event; ho...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Guo, Qiaoyan, Li, Xiaoxia, Han, Hongbo, Li, Chaoyuan, Liu, Shujun, Gao, Wenhui, Sun, Guangdong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876202/
https://ncbi.nlm.nih.gov/pubmed/27247942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6927234
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