PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome

PURPOSE: Classical Hodgkin lymphomas (cHLs) include small numbers of malignant Reed-Sternberg cells within an extensive but ineffective inflammatory/immune cell infiltrate. In cHL, chromosome 9p24.1/PD-L1/PD-L2 alterations increase the abundance of the PD-1 ligands, PD-L1 and PD-L2, and their furthe...

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Bibliografiska uppgifter
I publikationen:J Clin Oncol
Huvudupphovsmän: Roemer, Margaretha G.M., Advani, Ranjana H., Ligon, Azra H., Natkunam, Yasodha, Redd, Robert A., Homer, Heather, Connelly, Courtney F., Sun, Heather H., Daadi, Sarah E., Freeman, Gordon J., Armand, Philippe, Chapuy, Bjoern, de Jong, Daphne, Hoppe, Richard T., Neuberg, Donna S., Rodig, Scott J., Shipp, Margaret A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Clinical Oncology 2016
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ORIGINAL REPORTS
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019753/
https://ncbi.nlm.nih.gov/pubmed/27069084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.66.4482
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