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PD-L1 Expression is Characteristic of a Subset of Aggressive B-Cell Lymphomas and Virus-Associated Malignancies

PURPOSE: Programmed death ligand 1 (PD-L1) is an immunomodulatory molecule expressed by antigen-presenting cells and select tumors that engage receptors on T cells to inhibit T-cell immunity. Immunotherapies targeting the PD-1/PD-L1 pathway have shown durable anti-tumor effects in a subset of patien...

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Autores principales: Chen, Benjamin J, Chapuy, Bjoern, Ouyang, Jing, Sun, Heather H, Roemer, Margaretha GM, Xu, Mina L, Yu, Hongbo, Fletcher, Christopher DM, Freeman, Gordon J., Shipp, Margaret A, Rodig, Scott J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102335/
https://ncbi.nlm.nih.gov/pubmed/23674495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0855
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