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Preparation of novel pirfenidone microspheres for lung-targeted delivery: in vitro and in vivo study

The aim of this study was to develop and characterize pirfenidone (PF)-loaded chitosan microspheres for lung targeting. The microspheres were prepared using the emulsion-solvent evaporation method and characterized by assessing morphology, particle size, and zeta potential. The microspheres had a sp...

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Publicado en:Drug Des Devel Ther
Autores principales: Li, Dianbo, Gong, Liping
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019316/
https://ncbi.nlm.nih.gov/pubmed/27660413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S113670
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