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In situ delivery of thermosensitive gel-mediated 5-fluorouracil microemulsion for the treatment of colorectal cancer

In situ administration of 5-fluorouracil (5FU) “thermosensitive” gel effectively reduced systemic side effects in treating colon rectal cancer; however, the penetration efficacy of the formulation was considerably low due to the poor lipid solubility of 5FU. The aim of this study was to develop ther...

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Detalles Bibliográficos
Publicado en:Drug Des Devel Ther
Main Authors: Wang, Lu-Lu, Huang, Shuai, Guo, Hui-Hui, Han, Yan-Xing, Zheng, Wen-Sheng, Jiang, Jian-Dong
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019315/
https://ncbi.nlm.nih.gov/pubmed/27660416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S111351
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