Pamidronate Down-regulates Tumor Necrosis Factor-alpha Induced Matrix Metalloproteinases Expression in Human Intervertebral Disc Cells

BACKGROUND: N-containing bisphosphonates (BPs), such as pamidronate and risedronate, can inhibit osteoclastic function and reduce osteoclast number by inducing apoptotic cell death in osteoclasts. The aim of this study is to demonstrate the effect of pamidronate, second generation nitrogen-containin...

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Pubblicato in:J Bone Metab
Autori principali: Kang, Young-Mi, Hong, Seong-Hwan, Yang, Jae-Ho, Oh, Jin-Cheol, Park, Jin-Oh, Lee, Byung Ho, Lee, Sang-Yoon, Kim, Hak-Sun, Lee, Hwan-Mo, Moon, Seong-Hwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society for Bone and Mineral Research 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018610/
https://ncbi.nlm.nih.gov/pubmed/27622181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11005/jbm.2016.23.3.165
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