Mutation of orthologous prickle genes causes a similar epilepsy syndrome in flies and humans

OBJECTIVE: Genetically tractable fruit flies have been used for decades to study seizure disorders. However, there is a paucity of data specifically correlating fly and human seizure phenotypes. We have previously shown that mutation of orthologous PRICKLE genes from flies to humans produce seizures...

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Dades bibliogràfiques
Publicat a:Ann Clin Transl Neurol
Autors principals: Ehaideb, Salleh N., Wignall, Elizabeth A., Kasuya, Junko, Evans, William H., Iyengar, Atulya, Koerselman, Haley L., Lilienthal, Anthony J., Bassuk, Alexander G., Kitamoto, Toshihiro, Manak, J. Robert
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018582/
https://ncbi.nlm.nih.gov/pubmed/27648459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.334
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