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Structural and Functional Consequences of Chaperone Site Deletion in αA-Crystallin
The chaperone-like activity of αA-crystallin has an important role in maintaining lens transparency. Previously we identified residues 70–88 as a chaperone site in αA-crystallin. In this study, we deleted the chaperone site residues to generate αAΔ70–76 and αAΔ70–88 mutants and investigated if there...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018465/ https://ncbi.nlm.nih.gov/pubmed/27524665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2016.08.006 |
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