Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinomas.

Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcinoma (PHC) have identified a high frequency of codon 249 mutations. Due to the geographic location from which the samples were obtained and the substitution observed, the mutation was suggested to be at...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Buetow, K H, Sheffield, V C, Zhu, M, Zhou, T, Shen, F M, Hino, O, Smith, M, McMahon, B J, Lanier, A P, London, W T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9622
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