Comparative QSAR Analysis of 3,5-bis (Arylidene)-4-Piperidone Derivatives: the Development of Predictive Cytotoxicity Models

1-[4-(2-Alkylaminoethoxy) phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones are a novel class of potent cytotoxic agents. These compounds demonstrate low micromolar to submicromolar IC(50) values against human Molt 4/C8 and CEM T-lymphocytes and murine leukemia L1210 cells. In this study, a comparati...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Edraki, Najmeh, Das, Umashankar, Hemateenejad, Bahram, Dimmock, Jonathan R., Miri, Ramin
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018270/
https://ncbi.nlm.nih.gov/pubmed/27642313
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