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A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.

The 5' cap structure m7GpppN (where N is any nucleotide) is a ubiquitous feature of cellular eukaryotic mRNAs. The cap is multifunctional as it is involved in translation, nucleocytoplasmic transport, splicing, and stabilization of mRNA against 5' exonucleolytic degradation. The cap binding protein,...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lejbkowicz, F, Goyer, C, Darveau, A, Neron, S, Lemieux, R, Sonenberg, N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1384058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9612
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