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A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.

The 5' cap structure m7GpppN (where N is any nucleotide) is a ubiquitous feature of cellular eukaryotic mRNAs. The cap is multifunctional as it is involved in translation, nucleocytoplasmic transport, splicing, and stabilization of mRNA against 5' exonucleolytic degradation. The cap binding protein,...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lejbkowicz, F, Goyer, C, Darveau, A, Neron, S, Lemieux, R, Sonenberg, N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1992
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1384058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9612
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