A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect

The Warburg effect, or aerobic glycolysis, is marked by the increased metabolism of glucose to lactate in the presence of oxygen. Despite its widespread prevalence in physiology and cancer biology, the causes and consequences remain incompletely understood. Here, we show that a simple balance of int...

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Bibliographic Details
Published in:Biophys J
Main Authors: Dai, Ziwei, Shestov, Alexander A., Lai, Luhua, Locasale, Jason W.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2016
Subjects:
Systems Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018130/
https://ncbi.nlm.nih.gov/pubmed/27602736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.028
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