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A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect

The Warburg effect, or aerobic glycolysis, is marked by the increased metabolism of glucose to lactate in the presence of oxygen. Despite its widespread prevalence in physiology and cancer biology, the causes and consequences remain incompletely understood. Here, we show that a simple balance of int...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Dai, Ziwei, Shestov, Alexander A., Lai, Luhua, Locasale, Jason W.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018130/
https://ncbi.nlm.nih.gov/pubmed/27602736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.028
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