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Regulation of Nociceptive Plasticity Threshold and DARPP-32 Phosphorylation in Spinal Dorsal Horn Neurons by Convergent Dopamine and Glutamate Inputs

Dopamine can influence NMDA receptor function and regulate glutamate-triggered long-term changes in synaptic strength in several regions of the CNS. In spinal cord, regulation of the threshold of synaptic plasticity may determine the proneness to undergo sensitization and hyperresponsiveness to noxi...

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Veröffentlicht in:PLoS One
Hauptverfasser: Buesa, Itsaso, Aira, Zigor, Azkue, Jon Jatsu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017751/
https://ncbi.nlm.nih.gov/pubmed/27610622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162416
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