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p27(Kip1) Is Required to Mediate a G1 Cell Cycle Arrest Downstream of ATM following Genotoxic Stress

The DNA damage response (DDR) is a coordinated signaling network that ensures the maintenance of genome stability under DNA damaging stress. In response to DNA lesions, activation of the DDR leads to the establishment of cell cycle checkpoints that delay cell-cycle progression and allow repair of th...

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Pubblicato in:PLoS One
Autori principali: Cassimere, Erica K., Mauvais, Claire, Denicourt, Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017644/
https://ncbi.nlm.nih.gov/pubmed/27611996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162806
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