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p27(Kip1) Is Required to Mediate a G1 Cell Cycle Arrest Downstream of ATM following Genotoxic Stress
The DNA damage response (DDR) is a coordinated signaling network that ensures the maintenance of genome stability under DNA damaging stress. In response to DNA lesions, activation of the DDR leads to the establishment of cell cycle checkpoints that delay cell-cycle progression and allow repair of th...
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| Published in: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017644/ https://ncbi.nlm.nih.gov/pubmed/27611996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162806 |
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