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Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate

The rapid and strong clinical efficacy of the first-in-class, ingenol mebutate, against actinic keratosis (AK) has resulted in its recent approval. We conducted the first comprehensive analysis of the cellular and molecular mode of action of topical ingenol mebutate 0.05% gel in both AK and uninvolv...

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Publicat a:PLoS One
Autors principals: Emmert, Steffen, Haenssle, Holger A., Zibert, John R., Schön, Margarete, Hald, Andreas, Hansen, Maria H., Litman, Thomas, Schön, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017628/
https://ncbi.nlm.nih.gov/pubmed/27612149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160096
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