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Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate

The rapid and strong clinical efficacy of the first-in-class, ingenol mebutate, against actinic keratosis (AK) has resulted in its recent approval. We conducted the first comprehensive analysis of the cellular and molecular mode of action of topical ingenol mebutate 0.05% gel in both AK and uninvolv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Emmert, Steffen, Haenssle, Holger A., Zibert, John R., Schön, Margarete, Hald, Andreas, Hansen, Maria H., Litman, Thomas, Schön, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017628/
https://ncbi.nlm.nih.gov/pubmed/27612149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160096
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