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The Role of the Rho/ROCK Pathway in Ang II and TGF-β1-Induced Atrial Remodeling
OBJECTIVES: To study the role of the Rho/ROCK pathway in Ang II and TGF-β1-induced atrial remodeling. METHODS AND RESULTS: A canine atrial fibrillation (AF) model was established by rapid atrial pacing (RAP) of the left atrium. The roles of TGF-β1, the RhoA/ROCK signaling pathway and connective tiss...
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| Published in: | PLoS One |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017578/ https://ncbi.nlm.nih.gov/pubmed/27611832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161625 |
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