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Reversible off and on switching of prion infectivity via removing and reinstalling prion sialylation
The innate immune system provides the first line of defense against pathogens. To recognize pathogens, this system detects a number of molecular features that discriminate pathogens from host cells, including terminal sialylation of cell surface glycans. Mammalian cell surfaces, but generally not mi...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017131/ https://ncbi.nlm.nih.gov/pubmed/27609323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33119 |
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