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Reversible off and on switching of prion infectivity via removing and reinstalling prion sialylation

The innate immune system provides the first line of defense against pathogens. To recognize pathogens, this system detects a number of molecular features that discriminate pathogens from host cells, including terminal sialylation of cell surface glycans. Mammalian cell surfaces, but generally not mi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Katorcha, Elizaveta, Daus, Martin L., Gonzalez-Montalban, Nuria, Makarava, Natallia, Lasch, Peter, Beekes, Michael, Baskakov, Ilia V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017131/
https://ncbi.nlm.nih.gov/pubmed/27609323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33119
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