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Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response

Mitochondria, which are essential organelles in resting and replicating cells, can vary in number, mass and shape. Past research has primarily focused on short-term molecular mechanisms underlying fission/fusion. Less is known about longer-term mitochondrial behavior such as the overall makeup of ce...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Giedt, Randy J., Fumene Feruglio, Paolo, Pathania, Divya, Yang, Katherine S., Kilcoyne, Aoife, Vinegoni, Claudio, Mitchison, Timothy J., Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017129/
https://ncbi.nlm.nih.gov/pubmed/27609668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32985
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