Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations

BACKGROUND: The heterogeneity and tumourigenicity of metastatic melanoma is attributed to a cancer stem cell model, with CD133 considered to be a cancer stem cell marker in melanoma as well as other tumours, but its role has remained controversial. METHODS: We iteratively sorted CD133+ and CD133- ce...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Grasso, Carole, Anaka, Matthew, Hofmann, Oliver, Sompallae, Ramakrishna, Broadley, Kate, Hide, Winston, Berridge, Michael V., Cebon, Jonathan, Behren, Andreas, McConnell, Melanie J.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017126/
https://ncbi.nlm.nih.gov/pubmed/27613604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2759-2
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