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Structure-function analysis of Avian β-defensin-6 and β-defensin-12: role of charge and disulfide bridges

BACKGROUND: Avian beta-defensins (AvBD) are small, cationic, antimicrobial peptides. The potential application of AvBDs as alternatives to antibiotics has been the subject of interest. However, the mechanisms of action remain to be fully understood. The present study characterized the structure-func...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Yang, Ming, Zhang, Chunye, Zhang, Xuehan, Zhang, Michael Z., Rottinghaus, George E., Zhang, Shuping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016922/
https://ncbi.nlm.nih.gov/pubmed/27613063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0828-y
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