MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells

The efficiency of pluripotent stem cell differentiation is highly variable, often resulting in heterogeneous populations that contain undifferentiated cells. Here we developed a sensitive, target-specific, and general method for removing undesired cells before transplantation. MicroRNA-302a-5p (miR-...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Parr, Callum J. C., Katayama, Shota, Miki, Kenji, Kuang, Yi, Yoshida, Yoshinori, Morizane, Asuka, Takahashi, Jun, Yamanaka, Shinya, Saito, Hirohide
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016789/
https://ncbi.nlm.nih.gov/pubmed/27608814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32532
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