MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells

The efficiency of pluripotent stem cell differentiation is highly variable, often resulting in heterogeneous populations that contain undifferentiated cells. Here we developed a sensitive, target-specific, and general method for removing undesired cells before transplantation. MicroRNA-302a-5p (miR-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Parr, Callum J. C., Katayama, Shota, Miki, Kenji, Kuang, Yi, Yoshida, Yoshinori, Morizane, Asuka, Takahashi, Jun, Yamanaka, Shinya, Saito, Hirohide
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016789/
https://ncbi.nlm.nih.gov/pubmed/27608814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32532
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