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Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein

Retinal degeneration 3 (RD3) protein, essential for normal expression of retinal membrane guanylyl cyclase (RetGC) in photoreceptor cells, blocks RetGC catalytic activity and stimulation by guanylyl cyclase-activating proteins (GCAPs). In a mouse retina, RD3 inhibited both RetGC1 and RetGC2 isozymes...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016703/
https://ncbi.nlm.nih.gov/pubmed/27471269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742288
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