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ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces
Death domain superfamily members typically act as adaptors mediating in the assembly of supramolecular complexes with critical apoptosis and inflammation functions. These modular proteins consist of death domains, death effector domains, caspase recruitment domains, and pyrin domains (PYD). Despite...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016686/ https://ncbi.nlm.nih.gov/pubmed/27432880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.741082 |
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