Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase

Carotenoid cleavage dioxygenases (CCDs) are non-heme iron-containing enzymes found in all domains of life that generate biologically important apocarotenoids. Prior studies have revealed a critical role for a conserved 4-His motif in forming the CCD iron center. By contrast, the roles of other activ...

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Udgivet i:J Biol Chem
Main Authors: Sui, Xuewu, Zhang, Jianye, Golczak, Marcin, Palczewski, Krzysztof, Kiser, Philip D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016679/
https://ncbi.nlm.nih.gov/pubmed/27453555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744912
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