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Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases
Carotenoid cleavage dioxygenases (CCDs) use a nonheme Fe(II) cofactor to split alkene bonds of carotenoid and stilbenoid substrates. The iron centers of CCDs are typically five-coordinate in their resting states, with solvent occupying an exchangeable site. The involvement of this iron-bound solvent...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615678/ https://ncbi.nlm.nih.gov/pubmed/31138651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007535 |
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