Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division

The sterol regulatory element-binding protein (SREBP) transcription factors have become attractive targets for pharmacological inhibition in the treatment of metabolic diseases and cancer. SREBPs are critical for the production and metabolism of lipids and cholesterol, which are essential for cellul...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Gholkar, Ankur A., Cheung, Keith, Williams, Kevin J., Lo, Yu-Chen, Hamideh, Shadia A., Nnebe, Chelsea, Khuu, Cindy, Bensinger, Steven J., Torres, Jorge Z.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Accelerated Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016105/
https://ncbi.nlm.nih.gov/pubmed/27378817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.737346
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