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Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division

The sterol regulatory element-binding protein (SREBP) transcription factors have become attractive targets for pharmacological inhibition in the treatment of metabolic diseases and cancer. SREBPs are critical for the production and metabolism of lipids and cholesterol, which are essential for cellul...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gholkar, Ankur A., Cheung, Keith, Williams, Kevin J., Lo, Yu-Chen, Hamideh, Shadia A., Nnebe, Chelsea, Khuu, Cindy, Bensinger, Steven J., Torres, Jorge Z.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016105/
https://ncbi.nlm.nih.gov/pubmed/27378817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.737346
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