High-resolution mapping of mammalian genes by in situ hybridization to free chromatin.

Fluorescence in situ hybridization to metaphase chromosomes or chromatin fibers in interphase nuclei is a powerful technique in mapping genes and DNA segments to specific chromosome region. We have been able to release the chromatin fibers from cells arrested at G1 and G2 phases using different drug...

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Bibliographic Details
Main Authors: Heng, H H, Squire, J, Tsui, L C
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50161/
https://ncbi.nlm.nih.gov/pubmed/1384055
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