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High-resolution mapping of mammalian genes by in situ hybridization to free chromatin.

Fluorescence in situ hybridization to metaphase chromosomes or chromatin fibers in interphase nuclei is a powerful technique in mapping genes and DNA segments to specific chromosome region. We have been able to release the chromatin fibers from cells arrested at G1 and G2 phases using different drug...

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Detalhes bibliográficos
Main Authors: Heng, H H, Squire, J, Tsui, L C
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50161/
https://ncbi.nlm.nih.gov/pubmed/1384055
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