Innate recognition of cell wall β-glucans drives invariant Natural Killer T (iNKT) cell responses against fungi

iNKT cells are innate T lymphocytes recognizing endogenous and foreign lipid antigens presented in the MHC-like molecule CD1d. The semi-invariant iNKT cell TCR can detect certain bacterial and parasitic lipids, and drive iNKT cell responses. How iNKT cells respond to fungi, however, is unknown. We f...

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Publicado en:Cell Host Microbe
Autores principales: Cohen, Nadia R., Tatituri, Raju V.V., Rivera, Amariliz, Watts, Gerald F.M., Kim, Edy Y., Chiba, Asako, Fuchs, Beth B., Mylonakis, Eleftherios, Besra, Gurdyal S., Levitz, Stuart M., Brigl, Manfred, Brenner, Michael B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016029/
https://ncbi.nlm.nih.gov/pubmed/22100160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.09.011
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