Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition

Alpha1-antitrypsin (AAT) exerts its anti-inflammatory effect through regulating the activity of serine proteinases. This study evaluated the inhibitory effects of AAT against the transforming growth factor (TGF)-β1 induced epithelial-to-mesenchymal transition (EMT) in unilateral ureter obstruction (...

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Udgivet i:PLoS One
Main Authors: Cho, Jang-Hee, Ryu, Hye-Myung, Oh, Eun-Joo, Yook, Ju-Min, Ahn, Ji-Sun, Jung, Hee-Yeon, Choi, Ji-Young, Park, Sun-Hee, Kim, Yong-Lim, Kwak, Ihm Soo, Kim, Chan-Duck
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015906/
https://ncbi.nlm.nih.gov/pubmed/27607429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162186
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